See the Genetic Testing pages for more information. American Society of Clinical Oncology Statement: Of the 3 or 4 predictive factors suggested in the VNPI, the one which is most widely accepted as a useful predictor of local recurrence after breast-conserving surgery is the excisional margin the thickness of unaffected tissue removed along with the malignant tumor. Chi-squared tests were used to compare BCI results between age groups and clinical subsets. Add to My Bibliography. Comment in Wolfe mammographic parenchymal patterns and breast cancer risk. This test provides you and your doctor with information to help decide whether to extend or end anti-estrogen therapy beyond year 5 by analyzing your risk of breast cancer coming back after year 5 late recurrence and your likelihood of benefit from extending anti-estrogen therapy for an additional 5 years.
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Breast patterns as an index of risk for developing breast cancer.
Breast Cancer Index or BCI is a new test to help determine if you are likely to benefit from an additional five years of anti-estrogen medication. How this information is used to guide patient care is the responsibility of the physician. I am a patient or caregiver. The index initially looked at three factors commonly associated with DCIS aggressiveness. Food and Drug Administration.
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Breast Cancer Index (BCI)
Breast Cancer Res Treat. The Breast Cancer Index reports two scores: The Breast Cancer Index test is performed on preserved tissue that was removed during the original biopsy or surgery. It is generally accepted now that women with very small excisional margins are the most at risk and the most likely to benefit from radiation therapy. Because many women have troubling side effects, including hot flashes and joint pain, from hormonal therapy, they want to know if extending the time they take hormonal therapy is worth tolerating the side effects. The content on this website is intended for healthcare professionals.
Description:Conversely, hospitals might consider using the VNPI to help determine patients for whom the probable risk of local recurrence is so high, even with radiation therapy, that a mastecomy is recommended. Back to breast cancer staging list. The diagnosis and management of ductal carcinoma in-situ of the breast. This test is used for clinical purposes. Right now, the Breast Cancer Index test is not approved by the U. Last modified on July 24, at 6: